637例兒童血清病毒抗體檢測分析.pdf

1、蘭州大學碩士學位論文637例兒童血清病毒抗體檢測分析姓名：朱冬梅申請學位級別：碩士專業(yè)：小兒內科指導教師：朱保權20100501蘭州大學碩士學位論文ABSTRACTObjectiveToinvestigatecoxsackievirus、echovirus、respiratorysyncytialvirus，adenovirus，parainfluenzavirus，c”omegalovirus，rubeolavirusandhe印ss

2、implexvirusinfectioninchildreninLanzhouarea。MethodsThesamplesof637children(from3monthto16yearsold)inLanzhouareaduringtheperiodofFebruary2006toAugust2009，includingViralmyocarditisanddoubtful279cases，256healthychildren，wer

3、edetectedforcoxsackieBvirustypes12，3，4，5，coxsackieA，echovirustypes69，respiratorysyncytialvirus，adenovirustypes3，11，parainfluenzavirustypes23，cytomegalovirus，rubeolavirusandherpssimplexvirustype1altogether8viruses16typesb

4、ythecellculture。ResultsViralneutralizationantibodyweredetected，in315positiveresultsoutof637samplesandthepositiverateWas4945％，includingcoxsackieBvirus267positivecases(8476％)，C2Wastheprincipalviralpathogen謝thtotal90cases(2

5、857％)，thenC3C1was66cases(2059％)and57cases(1810％)Echoviruswas66cases(2095％)，E6wasthemajorviralpathogen，誦tlltotal44cases(1397％)Parainfluenzaviruswas159cases(5048％)，parainfluenzavirustype3wasthemajorviralpathogen晰mtotal82ca

6、ses(2603％)Adenoviruswas98cases(3111％)，adenovirustype11Wasthemajorviralpathogen，withtotal53cases(1683％)RespiratorysyncytialvirusWas52cases(165l％)Herpssimplexvirustype1Was70cases(2222％)CytomegalovirusWas34cases(1079％)Rubeo

7、lawas27cases(857％)Respiratorysyncytialviruswasdetected12cases(381％)ininfantsandyoungchildrenCoxsac虹eBvirusWasthemajorviralpathogeninchildrenfrom3yearsoldto7yearsold，晰tlltotal41cases(2485％)CoxsackieBvirusandparainfluenzaV

8、IRUSwerethemajorviralpathogeninchildrenfrom7yearsoldto14yearsold，誦tlltotal169cases(5045％)and105cases(3134％)CoxsackieBviruswasthemajorviralpathogeninchildrenfrom14yearsoldto16yearsold，withtotal53cases(6163％)Comparedimesti