四氟硼酸芳香重氮鹽作底物的Heck反應(yīng)及水相中的Heck反應(yīng)研究.pdf

1、江西師范大學(xué)碩士學(xué)位論文四氟硼酸芳香重氮鹽作底物的Heck反應(yīng)及水相中的Heck反應(yīng)研究姓名：胡榮華申請學(xué)位級別：碩士專業(yè)：有機化學(xué)指導(dǎo)教師：蔡明中2001.4.1江西師范大學(xué)學(xué)位論文AbstractInthispaper，wereviewedtheapplicationanddevelopmentofpal—ladiumcomplexinorganicsynthesisWestudiedtheHeckreactionofavariet

2、yofsubstitutedarenediazoniumtetrafluoroborateswhichwereeasierpreparedthanarylhalidesandtheHeckreactioninwaterPartone：Palladium—catalyzedethoxycarbonylationreactionofarenediazoniumtetrafluoroboratesproceededsmoothlyunderv

3、erymildconditioninthepresence0facatalyticamountofPd(OAc)2andCaOinethanoltoaffordavarietyofsubstitutedethylbenzoatesingoodyieldTheeffectsOfthecatalystandthebaseonethoxycarbonylationreactionwereinvestigatedandCaOwasshownto

4、bethebestbaseTheethoxycarbonyIationreactionprovidedasimpleandpracticalprocedureforsynthesesofavarietyofsubstitutedethylbenzoatesParttwo：Arylationreactionofallylicalcoholswitharenediazoni—umtetrafluoroboratesproceededsmoo

5、thlyinthepresence0facatalyticamountofPd(OAe)2inethanoltoaffordthecorrespondingp—arylalde—hydesorp—arylketonesinmoderateyieldsTheeffectsoftheamountofsolventandthereactiontemperatureonthearylationreactionwerein—vestigatedP

6、artthree：ArylationofacrylamideandacrylonitrilewerecarriedoutwithvariousarenediazoniumtetrafluoroboratesinthepresenceofacatalyticamountofPd(OAc)2inethanolandthecorresponding(E)一cinnamamidesand(E)一cinnamonitrileswereobtain

7、edinhighyieldsundermildreactionconditionsPartfour：Palladium—catalyzedarylationofallylicalcoholswitharyliodideswereshowntooccurinthepresenceofsodiumbicarbonateandtetranbutylammoniumchlorideinpurewaterusingpalladiumac——eta