X線照射對視神經(jīng)間接損傷后膠質(zhì)細(xì)胞影響的實驗研究.pdf

1、第一軍醫(yī)大學(xué)碩士學(xué)位論文X線照射對視神經(jīng)間接損傷后膠質(zhì)細(xì)胞影響的實驗研究姓名：吳建國申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：黃震晞2001.5.1ExperimentalstudyoftheeffectofXRayradiationonastrocyteafteropticnerveinjureindirectlyAbstractObjective：Thepurposeofthepresentstudyareasfollowings：①

2、MostcasesseeninclinicsarcindirectinjuriesItisallurgentneedteplicatetheanimalmodelforelucidationofthepathologicalCmll忑eandfordirectionofclinicaltreatmentofindireetopticneTceinjury②Throughcopyingthemodelofadultrabbit’Sopti

3、cnerveinjuryindirect職weinvestigatetheeffectofX—RayonreactiveastrocyteMethod：①Undergeneralanesthe$試thebilateralsupraorbitalnotchesandoIbitalwallsweresurgicallyexposedArectangulargaponeithersideoforbitalwallsWasmadebyexcis

4、ionofaportionoforbitallamina(smmdeepand6InlEtwidelfromsupra—orbitalnotchdownwardtotheopticforamen，SOtheunderlyingopticnerveWasleftintactThena2mlong、25mminnerdiameterselfmadetraumatictubeWasperpendicularlyplaced25lnnlabov

5、ethetraumaticclampLastly，arustlesssteelball，(weight45囂diameter2225mm)WasdroppedfreelyfromtheupperorificeofthetraumatictubeandhitupontheuppersurfaceoftraumaticclampOccurrenceoffixedpupildilmationincompanywithlossofdirectl

6、ightrefleximmediatelyafterthestruckWastakenascriteriaforasuccessfultraumaTheopticagaveOilthecontrolsideWasnotstruck②l，2，3，4weekafterinjuringindirectlyopticnerve，wegaveirradiationdoseof35，45，55GYonexperimentationgroup，obs