放療對伴腋窩淋巴結1～3個轉移T1-T2期乳腺癌術后的應用價值.pdf

1、新疆醫(yī)科大學碩士學位論文放療對伴腋窩淋巴結1~3個轉移T1T2期乳腺癌術后的應用價值姓名：謝楓申請學位級別：碩士專業(yè)：腫瘤學指導教師：木妮熱.木沙江200904新疆醫(yī)科大學醫(yī)學碩士學位論文新疆醫(yī)科大學醫(yī)學碩士學位論文2ValueofpastmastectomyradiotherapyinT1T2breastcancerpatientswith13postitiveaxillarylymphnodesPostgraduate:XIEFen

2、gSupervis:Associateprof.munire.mushajiangAbstractObjective：Toanalyzetheincidenceriskfactsfregionalnodalfailture（RNF）inT1T2breastcancerpatients（median44yearrange2865）with13positiveaxillarynodestreatedwithpostmastectomyrad

3、iotherapylimitedtotheregionalnodes.Methods：From1995to200082patientsweretreatedwithpastmastectomy（radicalmodifiedradical）radiotherapyconfinedtothesupraclavicular、internalmammaryaxillarylymphnodeswithamediandoseof50Gyin25f

4、ractionsover5weeks.Themediannumberofnodesexaminedwas11（range121）.Themedianlymphnodsrate（LNR）was16.67%（range5.26%100%）.Results：The5yearoverallsurvivalratewas90.1%75.6%respectively.The5yearRNFCWRwas12.19%9.76%respectively.

5、The5yearRNFinpatientswithLNR＜20%≥20%was5.88%22.58%（P=0.031）.The5yearCWRinthesubgroupswithLNR＜20%≥20%was3.92%19.35%（P=0.03）.LNRwastheonlyindependentprognosticfactfRNFCWRLNRchemotherapylessthanfourcyclesweretheindependentp

6、rognosticfactfoverallsurvivalratebymultivariateanalysis.Conclusion：InT1T2breastcancerpatientswith13positiveaxillarynodestreatedwithradicalmodifiedradicalmastectomyarelativelyhighincidenceofcheastwallrecurrenceisobservedi

7、nthesubgroup.Lymphnodesrateistheonlysignificantprognosticfactoflymphnodschestwallrecurrence.Fthesepatientspostoperativelymphaticdrainageareacheatwallirradiationshoudbeconsidered.Keywds：breastneoplasmsrediotheraphyprognos