保濕劑對(duì)干燥性皮膚中板層小體作用的研究.pdf

1、復(fù)旦大學(xué)碩士學(xué)位論文保濕劑對(duì)干燥性皮膚中板層小體作用的研究姓名：王寅申申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：皮膚病性病學(xué)指導(dǎo)教師：王俠生2001.5.1E行bctofmoisturizerOillamdlarbodyinxerosisAbstractDryskinabasicsymptomofmanyskindiseases(egicthyos噸psoriasisatopicdermatitiskeratodermiatylodespalmarisp

2、rogressive，palmareczyma)andisclinicallymanifestedasscales，epidermalproliferationpruritusandeVellseveredermatitisoreczymaMostofxerosisisrelatedtometabolismoflipidbarrieroraminoacid，especiallysynthesisofepidermallipidinwhi

3、chlamellarbodyplaysamajorroleDlyncssskinchangeswithclimateandrelativehumidity(RH％)Ourstudyinvestlgativedalterationoflamellarbodyindifferentkindofxerosis，inordertosearchfornewmoisturizerandprovidenewtherapy如fskincareprodu

4、ctsandthisdiseaseinthefuture82casesofdryskin(xerosis，ichthyosis，psoriasis，atopicdermatitis，l(日刊Dddmiatylodespalmarisprogressiveeczymanormalcona01)wereincludedinthestudyThesewhohadotherdiseasesorcomphiations，andthosewhoha

5、dusedcorticosteroidorothertopicalagentswereexcludedTherapeuticanalysis：82casesreceivetopicaltherapyof黼fffefllTl(conlrolgroup)andw／o／wtypebalTiermoisturizer(therapgroup)，andclinicalresponsewasevaluatedStatisticalanalysisW

6、flSconductancewithinandbetweenthegroupNoninvasivemeasuromentofconduction(“Q)of82xerosis腳e吣indicatedthatconductionwasmoreinpostaeatthaninpretreatTransmissioneleclroranicroscopyindicatedthatlamellarbodiesinthegranularlayer