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1、Imaging examinations of breasts,Department of radiology,Question,How to choose a proper examination for screening and diagnosis,?,?,What examinations we could use,Breast cancer,Higher incident rate of breast cancer for r
2、ecent yearsRisk factors: procreation, family history, environment, hormone ……Clinic findings:mass,skin changes The survival rate based on the stage of breast cancerScreening:ductal carcinoma in situ,Anatomy,15-18 lob
3、esLobules: Terminal Ductal Lobular Units (TDLUs),Anatomy,TDLU:1-2mmDrained by a terminal duct attached to the main duct systemMost breast diseases arise in TDLU,Imaging methods,MammographyUltrasoundMRI,Projection:
4、 CC MLO,Mammography,Mammographic characters,CalcificationMass,Calcification,PO43-,Calcium phosphat,,,,,Ca++,,,,Calcification,The main value : detection necrotic tissues Form: Casting type, powderish, gran
5、ular typeDifferentiation between malignant and benign: distribution, form, density,Calcification,Calcification,Calcification,Calcification,Mass,Proliferation and invasion Stellate lesion with spicules and ill-defined
6、borders Differentiation between malignant and benign is difficult,Mass,Mass,Mass,Mass,Characteristics of mammography,Sensitive to the malignant calcification even microcalcifications Differentiation between benign and
7、 malignant mass is difficult,Characteristics of Ultrasound Exam,Allows significant freedom in obtaining images from almost any orientationexcellent at imaging cysts and solid mass young women at high risk of the diseas
8、e Guide biopsy,Limited of ultrasound,Though ultrasound has excellent contrast resolution, it lacks the detail (spatial resolution) Operator and equipment factors unable to image microcalcifications,Benefits of MRI Exa
9、m,Allows breast images to be taken in any plane and from any orientationhighly sensitive to small abnormalities, could show multi-focal tumorDetermining the extent of breast cancer, can help indicate treatment An exce
10、llent at imaging the augmented breast,Limited of MRI Exam,Too expensiveCouldn’t find the microcalcification,Ductal Carcinoma in Situ,Intraductal carcinoma: cancer cells are confined to an intact basementmembrane Appe
11、arances: microcalcification (85%) microcalcification and mass (10%) mass or architectural distortion (5%),,Screening,P+ M+,operation,P+M-,ultrasound,Follow up,P-Ca+
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