鈍挫傷性近視動物模型的建立及相關(guān)指標的分析.pdf

1、青島大學(xué)碩士學(xué)位論文鈍挫傷性近視動物模型的建立及相關(guān)指標的分析姓名：王鋒申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：孔慶蘭20090531英文摘要AbstractObjective：TheresearchwastosetupananimalmodelofrabbitbasedontheSimulationofhumantraumaticmyopia，Intheanimalmodel，verifythedoctrineaboutEtiolog

2、yofthehumantraumaticmyopiaproposedbythecurrentdomesticandforeignscholars，detecttheseindicatorswithrelevantinstrumentsandmethods，andthentoanalyzethesignificanceofthevariousfactorsMethods：Beforetrauma，weSelected20rabbiteye

3、stodetectsomeindicators，suchasaxiallength，cornealthickness，refractivestatus，anteriorchamberdepth，lensthickness，etcandthenwehittherabbiteyeswiththesamefree—fallingsmallballtosetuptheideaanimalmodelbasedontheSimulationofhu

4、mantraumaticmyopiaFinallywere—measuredtherelevantindicatorsandanalyzedthedatabeforeandaftertraumatodeterminethereliabilityofanimalmodels，andanalyzedthesignificanceoftheindicatorsbyStatisticalmethodResults：Therefractivech

5、angeofrabbitsbeforeandafterthetraumahadsignificantstatisticalsignificance(PO01)，Inthefirstdayoftheposttraumatic，thechangofsomeindicators(suchasaxiallength術(shù)，cornealthickness木半，anteriorchamberdepth木，andlensthickness木)hadsi

6、gnificantstatisticalsignificancethanwhichinthepretrauma(幸掌P001，宰P005)，butinthe7thdayofthepost—traumatic，onlythechangoflensthicknesshadsignificantstatisticalsignificance(P005)UBMandhistopathologyshowed，Ciliarybodycompared

7、withthepretraumathattherealevaryingdegreesofedemainposttraumaticConclusion：Theexperimentalanimalmodelshasachievedthebasicideaasweexpected，intheearlyposttraumatic，Axiallength，cornealthickness，anteriorchamberdepth，lensthic