腦內(nèi)微出血的影像與臨床研究.pdf

1、南昌大學(xué)醫(yī)學(xué)院碩士學(xué)位論文腦內(nèi)微出血的影像與臨床研究姓名：王利申請學(xué)位級別：碩士專業(yè)：神經(jīng)病學(xué)指導(dǎo)教師：熊友生20070501ABSTRACTObjective：Inordertoinvestigatetheinfluenceofintracerebralmicrobleeds(IMBs)onstroke，weexaminedtheIMBsusingT2weightedgradientechoMRI(GRE—T2宰MRI)，compar

2、edthefrequencyandlocationofIMBsindifferentgroup，andstudiedtheassociationbetweenIMBsandvascularfactorsofstrokeMethods：100patientswithacutestroke，weredividedinto2groupsbyMRIexamination：lschemicgroup(n=50)orHemorrhagicgroup

3、(n=50)Comparedwiththecohortofnonstrokepatientsinthesameperiodwhowereolderthan50years(n=30)～lthepatientswereexaminedwithTlWI，T2WIandGRET2毒MRIroutinelyWerecordedthefreqyency，location，numberofIMBsandstrokelocation，leukoarai

4、osisWealsocollectedtheclinicaldatesuchashypertension，diabetesmellitus，heperlipemia，previousstrokehistoryforstrokepatientsStatisticalanalysiswasperformedwiththeStatisticalPackageofSocialSciences(SPSSinc)Result：IMBswereobs

5、ervedinallthethreegroups，andthefrequencyofIMBswere76％inhemorrhagicgroup，36％inischemicgroupand10％incontrolgroupMostofIMBsinischemicandcontrolgroupweremildandinhemorrhagicgroupweremoderateorsevereIMBsweremoreprevalentwithh

6、ypertension(p005)IMBswerecorrelatedwithleukoaraiosisQ001)ThecorrelationbetweenstrokelocationandIMBspredilectionsiteinhemorrhagicgroupissignificanthigherthanischemicgroupConclusion：ItwasrevealedthatthefrequencyofIMBswereS

7、Ohi【ghinstrokepatiente，especiallyinhemorrhagicstroke，andithasclosecorrelationwithhypertensionandstrokehistoryTheresultssuggestthatIMBshaveasignificantroleonprimaryintracerebralhemorrhageandhemorrhagictransformofischemics