不同孔隙度多孔鈦種植體對(duì)骨整合影響的研究.pdf

1、中南大學(xué)碩士學(xué)位論文不同孔隙度多孔鈦種植體對(duì)骨整合影響的研究姓名：鄭遙申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：口腔臨床醫(yī)學(xué)指導(dǎo)教師：陳良建20080501碩士學(xué)位論文英文摘要ABSTRACTobjective：nisstudyinvestigatedtheeffectofdifferentporosityontheosseointegrationofporoustitaniumimplantaftersurfacemodificationMateria

2、landmethod：ThisstudyutilizedtheMetalInjectionMoldingtechnologytoprepareporoustiantiumimplantswiththeporosityof40％and60％；cardedoutthesurfacemodificationbymeansofacid—baseheattreatment，biomimeticdepositionhydroxyapatite；im

3、plantedtheminthebackmuscleandfemurofdogs，nleanimalsweresacrificedat4，8，12weeksafterimplantationBoneformationintheimplantswasinvestigatedbyx—raytest，histologyandhistomorphometryofnondecalcifiedsectionsusingtraditionalligh

4、t—andfluorescencemicroscopy一Results：SofttissuesectionsusingHEstainingshowed：allofthebackmuscleimplantshadnoinflammationandnecrosisat4，8and12weeksnattwocolorfluorescentmarkersdetectionshowed：at4weeksaftertheimplantation，t

5、herewasfluorescencedepositiononthesurfaceofthehostboneneartheimplants，butthefluorescencedepositionontheimplantsWasnotobviousAt8weeksaftertheimplantation，itshowedthatthereWasfluorescencedepositionbothonthesurfaceandextern

6、alporesofporousimplantAt12weeks，forgroupA，therewasonlyfluorescencedepositionintheexternalporesofimplant；forgroupB，thefluorescencecallalsobefoundinthedeep—seatedporesNondecalcifiedsectionsdetected：at4week，thereWasagapbetw

7、eenimplantsandthehostboneintwogroups，thefibrousconnectivetissuecouldbeseeninthegapFor8weeksaftertheimplantation，thegapbetweentheimplantandthehostbonegotnarrowItcanbeseenthattheosteoidformedonthesurfaceandexternalporesoft

8、heimplantButtheporesofdeeperlayerswerefilledwithfibrousconnectivetissueAt12weeksafterimplantation，bothofgroupAandBhadcompletedtheosseointegrationThenewgrownbonetissueofgroupAonlygrewintotheexternalporesandonlyalittleoste

9、oidexistedinthedeep—seatedporesForgroupB，thevisiblewellcalcifiedbonetissueexistedintheporesbothsurfaceanddeeplayers，themicrangiumcouldbeseeninsideofitTheQuantitativehistologicaldeterminationshowed：after4weeksyfortwogroup