骨與軟組織惡性腫瘤術前介入治療結(jié)合新輔助化療的臨床應用研究.pdf

1、內(nèi)蒙古醫(yī)學院碩士學位論文骨與軟組織惡性腫瘤術前介入治療結(jié)合新輔助化療的臨床應用研究姓名：戴兵申請學位級別：碩士專業(yè)：影像醫(yī)學與核醫(yī)學指導教師：馬和平20090501TheresearchofclinicalapplicationinboneandsofttissuesarcomapreoperativeinterventionaltherapycombinedwithneoadjuvantchemotherapyAbstractObje

2、ctiveToApproachtheinterventionaltherapycombinationwithneoadjuvantchemo—therapyinthetreatmentofboneandsofttissuesarcomatherapeuticeffectAndtoevaluatetheinterventionaltreatmentcombinedwitllneoadjuvantchemotherapytocuratiob

3、oneandsofttissuesarcomabeforeoperationfromtheimprovementofclinicalsymptoms，imagingdiagnosis，pathologyandotherfactomMethodsToretrospectthe65patientswithboneandsofttissuesarcomahadbeenoperatedintheInnerMongoliaHosptialfrom

4、June1997toJune2007AllPatientshavebeenfollowedupComparetheresultsofthe35caseswhoweretreatedwithneo—adjuvantchemotherapycombinedwithinterventiontherapybeforetheoperations(whichwasGroupA)withthethoseoftheother30caseswhowere

5、justtreatedwithasimplepreoperativeneoadjuvantintravenouschemotherapy(whichWasGroupB)Result①ThepatientsGroupAweresufferedlesspainthanthoseinGroupB(P005)andthefanctionofthememberinGroupAarebetterthanitinGroupB(PO05)thetemp

6、eratureofthepositionswhichwereinpathologicalprocessinGroupAWaslowerthantheGroupB(PO01)②Theserumlevelsofbone—specificalkalinephosphatase(BALP)inGroupAsteppeddownandSOdidthelactatedehydrogenase(LDH)(PO01)③Theoperationtimei

7、nlimbsalvagesurgery，thebloodlossvolumeandthepostoperativewounddrainageinGroupAwerelessthantheGroupB④ThellI、1V—classnecrosispositiverateaftertumorresection(PO05)，pseud—ocapsuleformationrate(X—rayobservation)(P001)，complet

8、etumorresectionrate(Po05)intheGroupAweresignificantlybetterthanintheGroupB(9PatientswithprosthesisreplacementinthegroupAwith12monthkneefunctionscore，therecentkneefunctionSCOrearebetterthanitinGroupB(P005)@GroupAwithposto