影響胃癌術后預后及復發(fā)的多因素分析.pdf

1、天津醫(yī)科大學碩士學位論文影響胃癌術后預后及復發(fā)的多因素分析姓名：閆玉蘭申請學位級別：碩士專業(yè)：腫瘤學指導教師：巴一20100501天津醫(yī)科人學碩士學位論文AbstractObjective：ToanalyzetherelatedfactorsaffectingtheprognosisandrecurrenceofgastriccarcinomaafteroperationAndtoprovidescientificproofforrai

2、singthelongtermsurvivalrateofthepatientsbycontrollingthecrisisfactorsMethods：Thedateof877patientswhowerediagnosedbyPreoperativeandafteroperationfromJan2001toDec2005inTianjincancerhospitalwereinvestigatedretrospectively，a

3、ndtheyallunderwentoperationofgastriccarcinomaincludingstageI“_，III，88patientswerelosttobevisitedand169patientswhowerevisitedtecurrenceTheKaplanMeiermethodandlogranktestwereusedforunivariatecomparisonsofsurvivalMultivaria

4、teanalysiswasdonebytheCOXregressionmodelResult：AccordingtotheKaplanMeierandlog—rankmethods，depthoftumorinvasion，lymphnodemetastases，thesizeoftumour，diseasedregion，whetherornottotransferdistantplace，TNMstageandwhetherorno

5、ttogiveradicalsurgerywereprognosticfactorsMultivariateregressionanalysisindicatedthatonlylymphnodemetastases，whetherornottotransferdistantplace，TNMstageandwhetherornottogiveradicalsurgerywereindependentprognosticfactorsT

6、herewere878patientswhowerefolloweduptodeathorlosttobevisitedinthisgroup，themeansurvivaltimeWas475381277months(95％CI45034一50041)themediansurvivaltimeWas41750z：4594months(95％CI32746“50754)The13一and5yearcumulativesurvivalra

7、teswere8188％(646／789)、5131％(405／789)、4038％(318／789)，respectivelyButaccordingtotheKaplanMeierandlogrankmethods，thatlymphnodemetastasesandwhetherornottogiveradicalsurgerywasrelatedtecurrenceMultivariateregressionanalysisin

8、dicatedthatonlylymphnodemetastasesWasindependentenfluncedfactorThemeanrecurrencedtimewas248531882months(95％CI2116428542)，Themedianrecurrencedtime15000a：1898months(95％CI11281～18719)。The05一1and3yearcumulativerecurrencedrat