3800例嬰幼兒及兒童體外循環(huán)心臟手術并發(fā)急性腎損傷危險因素分析.pdf

1、中南大學碩士學位論文3800例嬰幼兒及兒童體外循環(huán)心臟手術并發(fā)急性腎損傷危險因素分析姓名：劉家軍申請學位級別：碩士專業(yè)：腎病內科指導教師：劉伏友20080501劉家軍碩士學位論文英文摘要ABSTRACTobjectiveTostudyriskfactorsassociatiedwithAKIinchildrenpatientsaftercardiacsurgerywithextracorporealcirculationMethodsA

2、restrospectivecasescontrolstudyWascardedoutinpatientswhoundwentcardiacsurgeryfrom2003to2007inOurhospital，with266patientsinAKIgroupand3534patientswithoutAKIascontrolgroupAllvariableswereanalyzedbyunivarietenanlysis，logist

3、icregressionorMannWhitneyUtestResultsAKIoccurredin340patients，研tllanincidenceof7％Univariateanalysisrevealedthatage，preoperativeserumcreatinine，preoperativeejectionfraction(EF)，preoperative132microglobulin，preoperativeblo

4、odabumin，preoperativeblooduricacid，intraoperativecardiopulmonarybypasstime，inteaoperativeaorticcross—clamptime，postoperativeintubationtime，postoperativehypotension，postoperativeoxygenpartialpressure(P02)，postoperativePHw

5、eresignificantlyrelatedtoAⅪfollowingcardiacsurgerywithextracorporealcirculationandlogisticmultivariateregressionanalysisshowedthatpreoperativeserumcreatinine(p0ooo)，preoperativeejectionfraction(EF)(pOooo)，preoperative92m

6、icroglobulin(p=0002)，preoperativeblooduricacid(p=O015)，intraoperativecardiopulmonarybypasstime(pOooo)，inteaoperativeaorticcrossclamptime(p0000)，postoperativehypotension(P=0027)，postoperativeIntubationtime(p0000)andpostop

7、erativeoxygenpartialpressure(P02)(PO000)wereindependentriskfactorsofAKIConclusionAge，preoperativeserumcreatinine，preoperativeejectionfraction(EF)，preoperative132一microglobulin，preoperativebloodabumin，preoperativeblooduri

8、cacid，intraoperativecardiopulmonarybypasstime，inteaoperativeaorticcross—clamptime，postoperativeIntubationtime，postoperativehypotension，postoperativeoxygenpartialpressure(P02)，postoperativePHweresignificantlyrelatedtoAKIf

9、ollowingcardiacsurgery、)~rithextracorporealcirculation，andlogisticmultivariateregressionanalysisshowedthatpreoperativeserumcreatinine，preoperativeejectionfraction(EF)，preoperative92一microglobulin，preoperativeblooduricaci

10、d，ntraoperativecardiopulmonarybypasstime，inteaoperativeaorticcrossclamptime，postoperativehypotension，postoperativeIntubationtimeandpostoperativeoxygenpartialpressure(P02)wereindependentriskfactorsofAKIKEYWORDS：extracorpo