不同濃度國產(chǎn)聚維酮碘對兔角膜毒性損傷的評價.pdf

1、浙江大學(xué)碩士學(xué)位論文不同濃度國產(chǎn)聚維酮碘對兔角膜毒性損傷的評價姓名：蔣勁申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：姚克20050301ofZhejiangUniversityHangzhou310004ChinaCorrespondingauthor：YAOKe，Email：xlren@zjueducn【Abstract10bjectiveToinvestigatethetoxiceffectofdifferentconcentratio

2、nsofpovidoneiodinemadeinChinaontherabbits’cornealepitheliaandendothelia，andtodiscussthefeasibilityandsuitableconcentrationofPVP—IusedasconjunctivalsacinstillationbeforeeyesurgeryoraftersurgeryMethodsgroupA，conjunctivalsa

3、cinstillationof5O％PVPI，assessedbymeansofspecularmicroscopyandcornealpachymetry；groupB，conjunctivalsacinstillationofdifferentconcentrationsofPVPIthedamageofcornealepitheliaisobservedafterfluorescencedye；groupC，theeffecton

4、endotheliaobservedaftertheinjectionsof005mlofdifferentconcentrationsofPVPIintotheanteriorchamberEachgroupiscomparedtoacorrespondingcontrolgroup一09％NSResultGroupA，therewasnosignificantdifferenceinthemainparametersobtained

5、between05％PVP—IandNS(p005)GroupB，severedamagewasobservedonthecornelepitheliaatconcentrationof5O％and25％butthecomeaisclearatconcentrationof1O％andO5％GroupCsignificantcornealedemawasobservedatconcentrationof20％and15％butthere

6、wasnosignificantdifferenceinthemainparametersbetween1O％andNSor05％andNSfj)005)ConclusionConsideringtheeffectonbothcornealepitheliaandendotheliaitissafeandfeasibletouse05％or1O％PVPIasconjunctivalsacinstillationforantisepsis