三維適形放射治療晚期胰腺癌的臨床意義.pdf

1、中國醫(yī)科大學(xué)博士學(xué)位論文三維適形放射治療晚期胰腺癌的臨床意義姓名：吳榮申請學(xué)位級別：博士專業(yè)：影像醫(yī)學(xué)與核醫(yī)學(xué)指導(dǎo)教師：郭啟勇2002.2.1Three—dimensionalconformaltechniquefortreatinglocallyadvancedpancreaticcancerintheclinicalmeaningAbstractPostgraduateforMDWuRongTutorGuoQiyongobject：

2、Weusethethree—dimensionalconfonnalof6myphotonstotreatpancreascancerandcomparewiththecommontechniques，throughtheclinicalbenefitresponseindexoftumormarketandimagephotochanges，andobservedthecurativeeffectMaterialandmethods：

3、Thisstudyfocuson15locallyadvancedpancreascancerpatients，applyingCTsimulationwiththethreedimensionalconformalsystemgettingtherecoveredimagephotostoobservetheinterspacelocationrelationsbetweenpathologicalchangesandkeyphysi

4、caloIgansItwassetupthetreatplansofthree—dhnensionalconfonnal，thecommonthree—fieldandfourfieldplanwiththemethodofusing6MVphotosItwascomparedtheaveragetargetvolume，theaverageorganswithdifferentdosages，andtheaveragedosagere

5、ceivedineachkeyorgansThestudywasusedthemedicallinearaccelerator，followthethree—dimensionalconformalplantotreatthelocallyadvancedpancreascancel“suffers，57Gyperdayandtreatoneanotherdaytotallyusing58kindsofmethods，totaltrea

6、tDr40—45GyThestudyalsoobservedthechangesoftumormarketofbloodserumCEA，CAl9—9，CA242andtheimagephotosResults：Thestudywasshownthatamongthethreemethods，itisnosignificancediff爸rent(P005)fortheaveragetmgetvolumeswiththedosageof

7、90％photonsForthetreatdosagebetween40％一50％，thetargetvolumesWaspositivelyreducebyapplyingthethree—dimensionaIconformaIthanthecommonthree—fieldandfomfieldtreatment(P005)，butthephotondosagereceivedbyspinalcordandleftkidneyha