DLEK和PK兩種術(shù)式治療大皰性角膜病變的對比實(shí)驗(yàn)研究.pdf

1、內(nèi)蒙古醫(yī)學(xué)院碩士學(xué)位論文DLEK和PK兩種術(shù)式治療大皰性角膜病變的對比實(shí)驗(yàn)研究姓名：羅云娜申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：趙海霞李惠敏20090501凼鏊直匿堂墮亟嬰窒生學(xué)位論3℃(2009年)TheContrastExperimentalStudyofDeepLameilarEndothelialKeratoplastyAndPenetratingKeratoplastyForBullousKeratopathyAbstrac

2、tObjectivesTocomparetheastigmatis、aUograftreactionandcornealshapeafterdeeplamellarendothelialkeratoplasty(DLEK)andpenetratingkeratoplasty(PK)forbullouskeratopathy(BK)inrabbitToevaluatetheastigmatismchangesafterdeeplameUa

3、rendothelialkeratoplastyMethods1Theestablishmentofrabbitmodel：almminjectionwasinsertedintotheanteriorchamberofthefighteyeviathecol“nea，lmmcentraltothelimbus，thenboththecornealendotheliumandtheDescmet’smembrane(DM)Wasscra

4、pedoff，don’tscathetheangleofanteriorchamberandlartsThecornealcloudinessandcomplicationwereassessedbyslitlampmicroscope2Twenty—fouradultrabbitswithBullouskeratopathy‘nedrandomlinto2Ingroup(iDLEK)，deelamellarendotheliwerea

5、smgnedrandomlyinto2groupsonegroup(groupDLEKdeeplamellarendotheli，alkeratoplasty(DLEK)wasperformedIntheothergroup(groupPK)，standardpenetratingkeratoplasty(PK)WasperformedAndtheallwereperformedthefighteyesoperationTOobserv

6、etheastigmatismandallograftreactionusecornealtopographyandslitlampmicroscopeafteroperation(in1month、2monthand3month)3IngroupDLEKandPK，cornealsampleswereexaminedbyHEstainingatthethirdmonthafteroperationResults1IngroupDLEK

7、，thecomeabeganclearingat2weeksafterthesurgeryin10ofthe12eyesThecorneawasdearat3monthafterthesurgery，thereWaSnotaintandcomplicationTheoperationfailedin2eyes，bc!causeofthelamella／perforationIngroupPK，9ofthe12o。Irneaswasdea