藥對(duì)麻黃-羌活、麻黃-生姜揮發(fā)油成分研究.pdf

1、中南大學(xué)碩士學(xué)位論文藥對(duì)麻黃羌活、麻黃生姜揮發(fā)油成分研究姓名：蘭正剛申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：生物化工指導(dǎo)教師：李曉如20070516ABSTRACTInthispapertheessentialoilswereextractedfromEphedrasinicaStapj《ES鰳，Notopterygiumme括umTing(NIT)，ZingiberofficinaleRose(ZOR)，anddrugpairsESSNITandES

2、SZORrespectivelyThechemicalcomponentsoftheseessentialoilswereanalyzedbygaschromatographymassspectrometry(GC—MS)togetherwithheuristicevolvimglatentprojections(HELP)methodThecomiiloncompoundsbetweentheindividualdruganddrug

3、pairwereanalyzedbythemethodnamedalternativemovingwindowsfactoranalysis(AMWFAlSixtycompoundsofESSwereidentifiedrepresenting6434％ofthetotalcontentamongwhichthemaincomponentswerepMenth1en8一ol／CloHl80(744％)；Benzylidenemalona

4、ldehyde／CioHs02(484％)；8B—HCed_ran8ol／Ct31260(405％)；Pentacosane／C25H52(215％)：5methyl一2一(1methylethylidene)一Cyclohexanone／CloHl60(263％)；FiftysixcompoundsofNITwereidentified，representing8325％ofthetotalcontent，amongwhichthem

5、aincomponentswere2，6，6trimethylBicyelo[311]hept2ene／C『IoHl6(2165％)；6，6dimethyl一2methylene—Bicyclo[311]heptane／CioHl6(1906％)；DLimonene／CloHl6(446％)；lmethyl4(1一methylethyl)14一Cyclohexadiene／CioHl6(374％)；4一methyl1(1methylet

6、hyl)3Cyclohexen—tol／CtoHl80(347％)；Sixty—onecompoundsofZORwereidentified；amongwhichthemaincomponentarc㈣()p—Citronellol／Ct0H200(2044％)；Camphene／CioHi6(1139％)；洳CitraYCoHl60(805％)；pCitral／CIoHt60(502％)；Sixtyfivecompoundsofdr

7、ugpairESSNITwereidentifiedrepresenting7569％ofthetotalcontent，amongwhichthemaincomponentswere26，6一trimethyl—Bicyclo[311]hept2ene／C10H16(1818％)；6，6dimethyl2一methylene—Bicyclo[311]heptane／CiOHl6(1533％)：1methyl一4一(1methyleth

8、yl)1，4一Cyclohexadiene／C；01116(328％)；DLimonene／CloHl6(313％)；Imethyl一4(1一methylethyl)Benzene／CIOHl4(279％)。砸r哆severcompoundsofdrugpairESSNITwereonlyfromNITeightcompoundswereonlyfromESS，tenlleWcompoundswereonlyinthedrugpairE