蒼白球腹后部毀損術(shù)治療帕金森病的療效分析.pdf

1、山西醫(yī)科大學(xué)碩士學(xué)位論文蒼白球腹后部毀損術(shù)治療帕金森病的療效分析姓名：段虎斌申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：神經(jīng)外科學(xué)指導(dǎo)教師：劉躍亭20040518山西醫(yī)科大學(xué)碩士學(xué)位論文A且analysisoflongtermcurativeeffectoftheposteroventralpallidotomyfortheParkinson’SDiseaseAbstractobjectiveToexplorethelongtermcurativeeffe

2、ctandsomelawsoftheposteroventralpallidotomy(PVP)fortheParkinson’sDisease(PD)MethodSeventy—ninepatientswithPDhadbeentrackedsince1998Inthesepatients，F(xiàn)ifry—eightpatients(pvFgroup)hadundergoneposteroventralpallidotomyandtwen

3、tyonepatients(nonPVPgroup)hadneveracceptedanysurgeryforPDThescoreofUnifiedParkinson’sDiseaseRatingScaleCLIPDRS)ofPVPgrouphadbeenrecordedbeforetheoperationandinlessthanIyear，lyear，2year3yearand4yearaftertheoperation，weals

4、ohadrecordedthescoreofUPDRSofnon—PⅦgroupatthetimeofvisitationandinlessthan1yearlyear2year3yearand4yearafterthevisitationTheresultsoffollow—upweTeanalyzedwitllstatisticsandstatisticsoRwareAcoordingtothesestatisticdata，wet

5、rytomakeascientificevaluationabouttheshorttermandlongtermcurativeeffectofPVPforthePDResultsTherearenotabledifferenceamongthescoreofUPDRSbeforePVPtheoneintheshorttermafterPVPandtheoneinthelongtermafterPVP(p‘O001)，Thelong—

6、termfollowupreviewshowthatthescoreofUPDRSofPVPgroupincreasemoreslowlythanthatofnonPVPgroup0005)TheshorttermeffectofPVP(j，I)hadrelationship謝t11theageatthetimeofoperation(X2)andtheseverityofPDbeforetheoperation(X6)Themulti

7、plelinearregressionequationsareasfollows：Y1_一6087O250X20424X6(onstate)，R2=0430；Yl一114590207X2o530X6(offstate)，R2=0609Thelong—termeffectofPVP(Y2)hadrelationshipwiththeshorttermeffectofPVPⅨOandthetimeoffollow—up(X4)。Themul