公駝寶克對大鼠子宮肌瘤治療作用的研究.pdf

1、分類號TS252.1學校代碼10129UDC663.1學號08209023公駝寶克對大鼠子宮肌瘤治療作用的研究StudyonTherapeuticEffectofPollGlSecretionsofBactrianCamelontheLeiomyomaUteriinRat申請人：王娟學科門類：工學學科專業(yè)：農產品加工及貯藏工程研究方向：乳品生物技術與加工工程指導教師：吉日木圖教授論文提交日期：二〇一一年四月StudyonTherapeu

2、ticEffectofPollGlSecretionsofBactrianCamelontheLeiomyomaUteriinRatAbstractObjective:Tostudythetherapeuticeffectofpollglsecretionsofbactriancamel(Camelusbactrianus)leiomyomauteriinrat.Methods:60SDfemaleratsweredividedroml

3、y5groupswhichincludenmalgroupmodelgroupgongliuxiaogrouppollyglsecretionshighgrouppollglsecretionslowergroup.Exceptthenmalgroupotherswasinjectedwithdiethylstilbestrolprogesteronetoestablishedtheratleiomyomauterimodel.Duri

4、ngthemodeltimediethylstilbestroltheprogesteronewasinjectedonceadaythreetimesaweek.After11weeksthenmalgroupthemodelgroupwasgivennmalsalinebyintragastricadministration.Thegongliuxiaogroupwasgiventheliquidofthegongliuxiaoby

5、intragastricadministration.Thepollglsecretionsgroupswasgivenpollglsecretionsbyintragastricadministration.Inaccdancewiththisdosef5weeks.Afterthatthe6ratsofeachgroupwascollectedthebloodinthefemalartery.Theremainratswasdoth

6、atbythesamewayafter2weeks.ThetestsindexesincludesserumE2ProFSHTNFαIL2NOSlevelsweightoftheuterusthespleen.thenmakeuterinepathologyfobservationthechangeinthat.Results:Thedateshowedthatafter11weekstheserumE2ProFSHTNFαIL2NOS

7、levelsofthemodelgroupswerehighlysignificantwiththenmalgroup(P＜0.01).Sothemodelestablishedsuccessfully.AfterthetreatmentthedateoftheE2ProFSHshowed7weeksofresultsofpollyglsecretionshighdosetreatmentgroupsignificantwiththep

8、athologicalmode(P0.01)notsignificantwiththecontrolgroup.Sothepollglsecretionsofbactriancamel(Camelusbactrianus)canreducetheserumsexhmonelevelsoftheleiomyomauterirats.TheresultoftheTNFαIL2showthatpollglsecretionshighdoset

9、reatmentgroupwhichtreatment7weekswassignificant(P0.01)withthepathologicalmodelnotsignificantwiththecontrolgroup.Sothepollglsecretionsofbactriancamel(Camelusbactrianus)canincreasetheserumlevelsofimmunefactsincreasetheimmu