分子腫瘤病理學(xué)及轉(zhuǎn)化研究的新進(jìn)展

1、<p>　　分子腫瘤病理學(xué)及轉(zhuǎn)化研究的新進(jìn)展 </p><p><b>　　[課程介紹]</b></p><p>　　本課程的授課目標(biāo)是為學(xué)生提供通過轉(zhuǎn)化醫(yī)學(xué)深入了解分子腫瘤病理學(xué)的途徑和方法。授課內(nèi)容將涉及多個(gè)腫瘤研究領(lǐng)域的新進(jìn)展，如miRNA, 腫瘤表觀遺傳學(xué), 上皮間質(zhì)轉(zhuǎn)化，腫瘤干細(xì)胞，新的癌基因和抑癌基因等。

2、分子腫瘤病理學(xué)與傳統(tǒng)腫瘤病理學(xué)不但相輔相成,而且能在傳統(tǒng)腫瘤病理學(xué)的基礎(chǔ)上進(jìn)一步發(fā)現(xiàn)新的腫瘤標(biāo)志物用于早期檢測，預(yù)測腫瘤的生物學(xué)行為及指導(dǎo)治療。</p><p>　　本課程中將會討論介紹多種分子生物學(xué)和病理學(xué)技術(shù)。例如FISH, 圖象分析, 定量PCR 和多種基于 PCR 的突變分析,和病理免疫組織化學(xué)的標(biāo)準(zhǔn)實(shí)驗(yàn)流程和結(jié)果解讀等。</p><p>　　本課程將鼓勵(lì)學(xué)生運(yùn)用轉(zhuǎn)化醫(yī)學(xué)的視點(diǎn)將基

3、礎(chǔ)分子病理學(xué)和臨床研究進(jìn)行整合分析。 </p><p>　　本課程將進(jìn)行13次授課，涉及分子腫瘤病理學(xué)和相關(guān)轉(zhuǎn)化醫(yī)學(xué)的多個(gè)前沿話題。 所有授課題目和授課教師請見附表. </p><p><b>　　[課程特色] </b></p><p>　　特色1：前沿性和交叉性。</p><p>　　特色2：橋梁性（注重基礎(chǔ)和臨床研

4、究的整合）</p><p>　　特色3：全部授課教師均有出國學(xué)習(xí)經(jīng)歷</p><p>　　Advances in Molecular Oncologic Pathology and Translational Research</p><p>　　[Description]</p><p>　　The goal of this course

5、is providing new insights into molecular oncologic pathology through translational research involving multiple cancer research filed, such as miRNA, Epigenetics, Epithelial mesenchymal transition, cancer stem cells, nove

6、l oncogenes and tumor suppressor genes etc. Complementary to and based on traditional diagnostic pathology, molecular oncologic pathology can serve to identify the novel biomarker for early detection of cancer, predict t

7、he biological behavior of a given tu</p><p>　　Multiple molecular biology and pathology techniques will be discussed in this course including: FISH, image analysis, quantitative PCR and RT-PCR and a variety o

8、f PCR based mutational analyses, and standard flowchart and result interpretation for immunohistochemistry.</p><p>　　This course should encourage students to develop a translational approach view to link bas

9、ic molecular pathology and clinical based cancer study. </p><p>　　In the body of the course, a series of 13 lectures will cover a wide range of advanced topics on translational research in molecular patholo

10、gy. All lecture topics and lecturers are attached below (Table 1). </p><p>　　[Features]</p><p>　　Feature 1: Cross-cutting and Cutting-edge </p><p>　　Feature 2: A bridging research