苗藥土黨參化學(xué)成分及其生物活性研究.pdf

1、Y737620貴州大學(xué)2005屆碩士研究生學(xué)位論文苗藥土黨參化學(xué)成分及其生物活。陛研究StudiesoNChemicalConstituentsandthorbloactJveofCampanumoeamwⅣk4學(xué)科專業(yè)：生擄此蘭丑盤王壘塑主研究方向：圭翅置世或垃班宜與藥物譴生指導(dǎo)教師；挪建壬越授揚塵生—班宜雖盎空運—敦—援研究生：韭直呈貴州大學(xué)2005屆頑士學(xué)位論文AIbstract：KeyWords：Campanumoeajavan

2、icaChemicalconstituentsPolysaccharideBioactiveStudyTostudythechemicalconstituentsofCampanumoeajavanicaCompoundswereextractedwithalcohol，distributedbydifferentsolvents，isolatedviamacroporousresinadsorbentandsilicacolumnch

3、romat刪ypunfiedbysilicagelchromatographyTheirstructureswereidentifiedbyphysicoehemicalpropertiesandspectralanalysesThirteencompoundswereobtainedfromtherootsofCampanumoeajavanicaandSevencompoundswereidentifiedasTangshenosi

4、de(I)Syriln百n(H)5Hyd】Iroxy46：7Trimethoxyftavorte(RI)，5Hydroxy4’7dimethoxyflavone(IV)，taraxerolacetate(V)friedelin(VI)andtaraxerol(vⅡ1AllofthemareisolatedfromCampanumoeajavanicaforthefirsttimeTostudytheisolationandcomposi

5、tionofPolysaccharideofCampanumoeaj￡tvanicaBLPolysaccharide(CJP一1，CJP2)CJPwaspurifiedbyDEAEandsepharosecThecomponentofthesacchridewasdeterminedbyGCandTLCItsMWwasmeasuredbygelfiltrationTheformofglucosidicbondWRSdetrermined

6、by皿ThecontentofthesaccharidewasmeasuredbycolorimetryCJP一1’Ssugarcompositioncomprises：Galactose，mannoge，glucoseWitharateof1：31：64AnditsaverageMWWaSmensuratedtobe39233x10’，CJP一2’ssugarcompositioncomprises：Xylose，Rhamnose，a

7、rabinose，marmose，Galactose，glucoseWitharateof1：16：37：17：64：140ItsaverageMWwasmensuratedtobe72147x103TypicalabsorptionofpolysaccharidewasshowninitsIRspectrum，ItcontainedoghicosideicbondsbyIRanalysisIthadnotypicalabsorptio