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1、目的:通過(guò)對(duì)超聲測(cè)定頸動(dòng)脈的改變分析高血壓,高尿酸血癥,動(dòng)脈粥樣硬化之間的關(guān)系,探討尿酸在動(dòng)脈粥樣硬化發(fā)生發(fā)展中的作用。
方法:分析151例在瑞康醫(yī)院心內(nèi)科住院治療的高血壓患者的病例資料,應(yīng)用生化分析儀檢測(cè)其血尿酸情況并行彩色多普勒超聲檢查以明確頸動(dòng)脈病變情況,根據(jù)其結(jié)果進(jìn)行分組研究。并根據(jù)彩色多普勒超聲檢查結(jié)果,按患者性別分組,以探討性別因素對(duì)頸動(dòng)脈病變的影響。
結(jié)果:采用計(jì)算機(jī)Microsoft Excel和PE
2、MS3.1軟件包進(jìn)行統(tǒng)計(jì)學(xué)分析,選取α=0.05篩選變量,計(jì)數(shù)資料數(shù)據(jù)用均數(shù)±標(biāo)準(zhǔn)差表示,組間計(jì)數(shù)資料用卡方(x2)檢驗(yàn),計(jì)量資料用t檢驗(yàn)。分別比較高血壓伴高尿酸血癥組與單純高血壓組及正常對(duì)照組頸動(dòng)脈形態(tài)學(xué)指標(biāo)有無(wú)統(tǒng)計(jì)學(xué)差異。結(jié)果顯示:高血壓組中檢出頸動(dòng)脈改變者占81.8%;高尿酸血癥組中檢出頸動(dòng)脈改變者占84.1%,兩組患者頸動(dòng)脈粥樣硬化的發(fā)生率較健康對(duì)照組明顯增加(P<0.05),而高血壓及高尿酸血癥兩組相比較其結(jié)果無(wú)顯著性差異(P
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